However, in the ovarian cancer microenvironment, TAMs generally exhibit the M2-like phenotype, with high expression of scavenger receptor class B (CD163), mannose receptor (MR, CD204) that serves as markers and immunosuppressive factors, including interleukin-10 (IL-10), as well as chemokines CCL18 and CCL22. The gene discussed is IL10; the disease is ovarian cancer.