While NLRP3 is necessary for anticancer adaptive immune responses, its activation has also been related to several types of cancer due to the release of IL-1β and IL-18; including CRC, CAC, fibrosarcoma, transplantable tumour, lung cancer, thymoma, gastric cancer, hepatocellular carcinoma, breast tumours, head and neck cancers, prostate cancer, cervical cancer and central nervous system tumours [83,84]. This evidence concerns the gene NLRP3 and colorectal carcinoma.