In addition, Kruppel-like Factor 6 (KLF6); a tumour suppressor through regulation of the p21Cip1 cyclin-dependent kinase inhibitor [127,128], has been identified as a novel DNA-binding partner of AhR to express inducible-TCDD when bound at the non-consensus XRE [129,130]. This evidence concerns the gene AHR and neoplasm.