In the cancer hallmark dataset, the number of co-expressed genes in the CHRNB4-high subgroup was equal to or greater than that in the CHRNB4-low subgroup (Figure 3B), and 11 enriched KEGG pathways (hypergeometric test p < 0.05 and ≥3 genes involved in pathways/modules) were identified for the CHRNB4-high subgroup but none were identified for the CHRNB4-low subgroup. The gene discussed is CHRNB4; the disease is cancer.