TGFB1 and Alzheimer disease: A higher plasma and CNS levels of inflammatory markers known as Interleukin-6 (IL-6), Interleukin 1β (IL-1β), transforming growth factor-β (TGF-β), and tumor necrosis factor-α (TNF-α) has been reported in AD patients, which indicates the potential role of inflammatory markers in AD pathogenesis [48].