Although IFN-γ increased FTMT mRNA expression to a greater level than TNF-α in ARPE-19 cells, as myeloid cells, not T-lymphocytes (source of IFN-γ), are observed in AMD and TNF-α has been implicated in AMD inflammation [15], our further studies employed TNF-α. The gene discussed is FTMT; the disease is age-related macular degeneration.