To this point, we re-analyzed the trends for traditional cardiometabolic risk markers (i.e., proxy measures of obesity, glucose homeostasis, lipid profile) as well as those of oxidative status, inflammatory markers, renal function, concentrations of uric acid, adiponectin, and sRAGE across BP categories separately in males and females. This evidence concerns the gene ADIPOQ and obesity due to melanocortin 4 receptor deficiency.