Hence, in males, variables characterizing obesity status, insulin sensitivity, atherogenic dyslipidemia, concentrations of uric acid, adiponectin, sRAGEs, and leukocyte counts showed worsening trends across BP categories while females presented significant trends only for obesity measures, LDL-C, and non-HDL-cholesterol. Here, ADIPOQ is linked to obesity due to melanocortin 4 receptor deficiency.