FOS and Anxiety: In this anxiety-inducing situation, after a single IP injection of 1 mg/kg of α-CZP, c-Fos expression decreased in the hippocampal formation, accumbens nucleus, dorsomedial, paraventricular and ventromedial nuclei of the hypothalamus, and bed nucleus of the stria terminalis (BNST), and increased in the amygdala [16].