With the third treatment (45 days after infection), the production of IL-6 in the group treated with TcSSP4 gene was significantly increased by 4-fold above the SS mock-treated infected group while the TcSP gene, the mixture of both plasmids, and the pBK-CMV empty plasmid induced similar levels of this cytokine to those of the infected/SS mock-treated group (Figure 3(b)). This evidence concerns the gene IL6 and infection.