AVP and ductal breast carcinoma in situ: The mean and SD of the collagen density were 0.86 ± 0.06 for normal breast tissue, 0.67 ± 0.09 for ADH, 0.57 ± 0.137 for low-grade DCIS, and 0.42 ± 0.162 for high-grade DCIS-MI.