To this aim, we studied the polymorphisms IL-1β-511C/T (rs16944), IL-6-174G/C (rs1800795), TNF-α-1031T/C (rs1799964), and TGFβ1-509T/C (rs1800469) to assess the association of these polymorphisms in RSA patients with or without PCOS. The gene discussed is IL6; the disease is polycystic ovary syndrome.