GSEA indicated that pathways in cancer, TGF-beta signaling pathway, JAK-STAT signaling pathway, Wnt signaling, Toll-like receptor signaling pathway, small cell lung cancer, prostate cancer, mTOR signaling pathway, oxidative phosphorylation, and T cell receptor signaling pathway are differentially enriched in PTPN6 high expression phenotype. The gene discussed is PTPN6; the disease is cancer.