STAT3 and acute lung injury: Wang et al. [23] found that the physiological and pathological conditions of septic acute lung injury (ALI) in QBD rats were significantly better than those of the model group (including pathological injury, pathological score, respiratory function, mental state and mortality, etc.), and the expressions of JAK2, p-JAK2, STAT3, p-STAT3, IKKα and NF-κBp65 protein in lung tissue of rats in QBD group were significantly down-regulated.