Conventional therapy combined with QBD in the treatment of sepsis (syndrome of flaring heat in qifen and xuefen) has effects on reducing the serum immunological indexes such as IgG, IgA, IgM, C3, CRP and TNF-α, reducing Acute Physiology and Chronic Health Evaluation II (APACHE II) score, as well as improving the effective rate of clinical treatment with good clinical effect, which is worth popularizing in clinical [17, 18]. The gene discussed is TNF; the disease is Sepsis.