CD4 and Hepatic fibrosis: In addition, CD4+T cell count was significantly increased after the completion of the treatment compared to that of the pretreatment in the NAs + FZHY group, and the numbers of NK cells were significantly increased in the patients at the posttreatment in the NAs + FZHY group, indicating that the underlying mechanisms of FZHYC effects on hepatic fibrosis are associated with immunologic modulation.