qRT-PCR showed that the mRNA expression of the key renal fibrosis factors TGF-β (88.49 ± 7.54, P < 0.01) and α-SMA (P < 0.01) was significantly higher in the UUO group than in the sham group, while the expression of TGF-β (88.49 ± 7.54, P < 0.01) and α-SMA (38.62 ± 7.41,P < 0.01) was decreased in the NDK mixture groups NDK-H (TGF-β, 4.62 ± 0.71, P < 0.05; DSMA, 2.87 ± 0.34, P < 0.01), NDK-M (TGF-β, 2.28 ± 0.62, P < 0.01; α-SMA, 1.51 ± 0.18, P < 0.01), and NDK-L (TGF-β, 2.61 ± 0.65, P < 0.05; α-SMA, 4.08 ± 0.32, P < 0.05) (Figure 1(i)). Here, ACTA1 is linked to renal fibrosis.