Qi Jianyong et al. further carried out experiments in H9C2 cells and found that Xinmailong Injection can inhibit the phosphorylation of ERK1/2, AKT, and glycogen synthase kinase 3β (GSK3β) associated with cardiac hypertrophy and further inhibit the overexpression of the low downstream factor GATA4 in the nucleus. This evidence concerns the gene GSK3B and cardiac hypertrophy.