MAPK3 and cardiac hypertrophy: Qi Jianyong et al. further carried out experiments in H9C2 cells and found that Xinmailong Injection can inhibit the phosphorylation of ERK1/2, AKT, and glycogen synthase kinase 3β (GSK3β) associated with cardiac hypertrophy and further inhibit the overexpression of the low downstream factor GATA4 in the nucleus.