AKT1 and staphylococcus aureus infection: The buried bivalve-specific gene families were enriched in 107 GO terms and 80 KEGG pathways (see Tables S25, S26, and S27; Figure 2B), mainly in association with a number of complex signaling systems (such as PI3K-Akt, Ras, Rap1, cAMP signaling, and calcium signaling pathways), ion binding (such as “zinc ion,” “transition metal ion,” “metal ion,” “cation,” and “calcium ion binding”), and the immune system (such as “Staphylococcus aureus infection,” “inflammatory mediator regulation of TRP channels,” and “salivary secretion”) (see Table S28).