By analyzing the GWAS Central database (https://www.gwascentral.org) [32], we found that several genetic polymorphisms in SLC2A10 locus are modestly associated with multiple T2DM-related phenotypes, including fasting plasma glucose, fasting insulin and body mass index in non-diabetic populations of independent human populations and studies (S1 Table). Here, INS is linked to type 2 diabetes mellitus.