Irgm1-/- mice develop robust colitis-associated pathology upon treatment with dextran sodium sulfate (DSS colitis)[17] and given that C. rodentium infected Irgm1-/- mice poorly controlled pathogen outgrowth and displayed heightened mortality and exaggerated weight loss, we hypothesized that the intestine of C. rodentium infected Irgm1-/- mice would also display exaggerated histologic pathology. Here, IRGM is linked to colitis.