HIF1A and Cerebral ischemia: Our findings demonstrated significantly up-regulated *(P < 0.05) expression of the toxic Aβ mOC64 form, APP, HIF-1α, as well as p-Tau in the brains of various groups of patients infected with HIV (asymptomatic as well as minor cognitive impairment, AD, cerebral ischemia) compared to uninfected individuals.