In a previous report, da Costa et al. (2008) showed thatseven unrelated carriers of this mutation share the same haplotype of genetic markeralleles flanking BRCA1. However, data available in Brazil regarding thefrequency of different pathogenic variants in individuals at risk of hereditarybreast/ovary cancer and the availability of samples from the c.5266dupC mutationcarriers limited the conclusions at that time with respect to a possible founder effect.In addition, da Costa et al.(2008) did not evaluate the ancestry of the carriers. Here, BRCA1 is linked to ovarian cancer.