Thus, the current study aimed toscreen the Punjabi population from Amritsar and adjoining regions of Punjab, NorthIndia, for the four variants of BRCA1 [c.190T>C (p.Cys64Arg),1307delT, g.5331G>A (p.G1738R) and c.2612C>T (p.Pro871Leu)] to investigatetheir association with breast cancer risk. Here, BRCA1 is linked to breast cancer.