In colon cancer cells (HCT116), the expression of miR-34a-5p hasbeen reported to induce apoptosis, cell cycle arrest at G1 stage and transcriptionof P53 (Gao et al., 2015).Hence, based on previous reports and the results from the current study, it can beimplicated that the RAD9A regulation by miR-34a-5p may affect theprogression of OS through cell cycle regulation. This evidence concerns the gene TP53 and colonic neoplasm.