The association was similar after removing participants with ApoE e4 associated diseases that were also linked to COVID-19 severity: participants without dementia (OR = 2.39, 95% CI: 1.71 to 3.35); hypertension (OR = 2.41, 95% CI: 1.56 to 3.74); coronary artery disease (myocardial infarction or angina) (OR = 2.43, 95% CI: 1.69 to 3.50) or type 2 diabetes (OR = 2.51, 95% CI: 1.77 to 3.55) (Table 1), based on preexisting diagnoses from baseline self-reports or hospital discharge statistics (updated to March 2017). Here, APOE is linked to type 2 diabetes mellitus.