In order to explore the effect of colitis on TRPA1 expression and sensitivity at the sensory neuron level, we examined the effects of DSS treatment on the relative expression of TRPA1 mRNA in lumbosacral DRGs and TGs (study 2, set 1) and on TRPA1 responsiveness of DRG neurons in culture (study 2, set 2). The gene discussed is TRPA1; the disease is colitis.