Of these, 486 cycles did not meet the inclusion criteria (279 cycles performing natural cycle or mild stimulation protocol for endometrial preparation, 104 cycles performing artificially prepared FET cycle with GnRH agonists pretreatment before steroid administration, 92 cycles in which no good-quality embryo was transferred and 11 cycles in which the age of patients at the (index) oocyte retrieval patients was more than 43 years) and 29 cycles were excluded for the patients suffering from endometriosis. The gene discussed is GNRH1; the disease is endometriosis.