VEGFA and wet macular degeneration: Anti-vascular endothelial growth factor (anti-VEGF) agents, such as intravitreal aflibercept (IVT-AFL) and ranibizumab, are available for the treatment of neovascular age-related macular degeneration (nAMD), and the goal of disease management beyond the first year is to maintain or improve functional and anatomical gains while minimizing the burden on patients of clinic visits and injections [2].