LncRNA HEIH was first reported to be upregulated in hepatocellular carcinoma.8 Moreover, HEIH was observed to facilitate cell proliferation, invasion and migration capability in melanoma.9 Guo et al. 10 found that upregulation of HEIH enhanced chemoresistance of paclitaxel, and promoted cell viability by activating the MAPK pathway in endometrial cancer. The gene discussed is HEIH; the disease is hepatocellular carcinoma.