TARDBP and proteostasis deficiencies: Such proteinopathies are identified by the presence of full‐length TDP‐43, polyubiquitinated TDP‐43, phosphorylated TDP‐43, and 35‐ and 25‐kDa carboxyl TDP‐43 fragments in the cytosolic/nuclear inclusions (Arai et al, 2006; Chen‐Plotkin et al, 2010).