Baicalein instead increased levels of stem cell factor (SCF), macrophage inflammatory protein-3 (MIP-3α), and transforming growth factor-beta 2 (TGF-β2) in both MM and OM, and increased the concentration of transforming growth factor-beta 3 (TGF-β3) and osteopontin in OM. The gene discussed is SPP1; the disease is ocular melanoma.