The DEGs induced by ChIFN-λ in both DF1 and LMH are mainly enriched in “response to other organism”, “response to external biotic stimulus”, “immune effector process”, “immune system process” for GO terms and “Herpes simplex infection”, “Influenza A”, “Jak-STAT signaling pathway” and “RIG-I-like receptor signaling pathway” for KEGG pathways (Additional files 6E–H). Here, SOAT1 is linked to herpes simplex infectious disease.