TWIST1 and familial pancreatic carcinoma: Previously, Liu et al. [10], have shown that overexpression of miR-1271 inhibits cell proliferation, invasion, migration, and tumor metastasis by binding to zinc-finger Ebox binding homeobox 1 (ZEB1) and twist family bHLH transcription factor 1 (TWIST1) in pancreatic cancer, highlighting that miR-1271 can function as a marker for treatment and prognosis of metastatic pancreatic cancer.