Moreover, in comparison with the mice inoculated with cells co-treated with sh-NC and NC antagomir, mice inoculated with cells co-treated with sh-PES1 and NC antagomir had decreased PES1 mRNA expression and reduced tumor growth rate and tumor volume, which was negated by co-treatment with sh-NC and miR-1271 antagomir (both p < 0.05). This evidence concerns the gene PES1 and neoplasm.