Across PTCL subtypes, systemic ALCLs universally express CD30 in membrane and golgi patterns, while approximately 50% of non-ALCL subtypes, including PTCL, NOS, AITL, ENKTL, ATLL, EATL, and HSTL, express CD30 at variable levels. The gene discussed is TNFRSF8; the disease is mature T-cell and NK-cell non-Hodgkin lymphoma.