Based on the above animal analysis, we could preliminarily know that PFD had a positive attenuating effect on BLM-induced pulmonary fibrosis, which was mainly achieved by inhibiting the phosphorylation of GSK-3β S9 and inactivating TGF-β1/Smad2/3 signaling pathway. This evidence concerns the gene TGFB1 and pulmonary fibrosis.