TNF and polyostotic fibrous dysplasia: Through the detection of ELISA assays, we found that the levels of inflammatory factors TNF-α and IL-6 in the supersolution of mice lung tissues in model group were obviously increased, which were notably suppressed after treatment with PFD; whereas over-expression of β-catenin reversed the inhibiting effect of PFD on inflammatory factor release and thus elevating the levels of TNF-α and IL-6 in lung tissue supersolution (P < 0.05, Fig. 1c and d).