SLC1A2 and Epileptic encephalopathy: Other altered genes in this patient that may cause diseases due to haploinsufficiency include BDNF, CAPRIN1, KCNA4, LGR4, and SLC1A2. Recently, Xu et al. reported that deletion of SLC1A2, PRRG4, and BDNF may be involved in abnormal psychological development [10] (e.g., early epileptic encephalopathy).