NR4A1 and neoplasm: Elevated MMP9 cytoplasmic and stromal staining were associated with high tumour grade (p < 0.0001), poor Nottingham Prognostic Index (NPI) (p < 0.0001; Table 1), hormone receptor negativity (p < 0.01), among IHC subtypes associated with TNBC and HER2 + tumours (p = 0.002).