Using oPOSSUM 3.033, genes increasing between day 1 and day 7 in patients with none or mild BPD were more likely to contain motifs predicted to bind NKX2-5, ARID3A, HOXA5, PDX1, NKX3-1, and FOXD3 (Fig. 5g). This evidence concerns the gene FOXD3 and bronchopulmonary dysplasia.