PDK4 and cancer: Combining our previous data that the YTHDF1 and eEF-2 interaction, but not eEF-1, significantly suppressed in Mettl3Mut/- HeLa cells than that in control cells12, the data hinted that both YTHDF1 and eEF-2 are likely associated to regulate the m6A induced translation elongation of PDK4 mRNA in cancer cells.