For example, the host gene lncRNA ZFAS1, which encodes three C/D box SNORD12 family members (SNORD12, SNORD12B, SNORD12C), was observed to be significantly overexpressed in a variety of human malignancies such as colorectal cancer, hepatic cancer, and gastric cancer, etc. [23–27]. This evidence concerns the gene ZFAS1 and colorectal cancer.