Similar results were obtained from 30 pairs of CRC tissues and matched tumor-adjacent normal tissues, where an elevated expression of ZFAS1 in CRC tissues and a further consistently up-regulated of SNORD12C, SNORD78, and NOP58 were detected by RT-PCR and qPCR assays (Fig. 2c, Fig. S2). This evidence concerns the gene NOP58 and colorectal carcinoma.