ZEB1 and posterior cortical atrophy: The EMT in PCa is activated by four mediators of snail, slug, twist, and Zinc finger E-box-binding homeobox 1 (ZEB1), while four signaling pathways play dominant roles here: the transforming growth factor (TGF) receptor (TGFR)/mothers against decapentaplegic homolog (Smads)/mitogen-activated protein kinase (MAPK) signaling cascade, nuclear factor (NF)-κB signaling, and the receptor tyrosine kinase (RTK) cascade [9].