Clinical criteria are useful for diagnosing FH and selecting patients for genetic testing of three genes coding for proteins that are involved in the clearance of LDL-C from blood: LDL-receptor (LDLR), apolipoprotein B (APOB), and pro-protein convertase subtilisin kexin 9 (PCSK9) [2,6,7,8]. This evidence concerns the gene LDLR and familial hyperaldosteronism.