In CD8 T cells, TCR DP04chim transfected cells showed strong IFN-γ production upon co-incubation with HLA-DPB1*04:01 positive AML sample 111 and EBV-LCL, but only weak (AML121) or no (AML128) recognition of other HLA-DPB1*04:01 positive AML blasts (Figure 1B, right panel). This evidence concerns the gene IFNG and acute myeloid leukemia.