HLA-DPB1 and acute myeloid leukemia: Here, both TCR DP04chim redirected CD4 and CD8 T cells showed highly specific lysis of HLA-DPB1*04:01 expressing AML blasts (AML111, AML121, AML128), while sparing an HLA-DPB1*04:01 negative sample (AML110) (Figure 1C).