GC and polycystic ovary syndrome: In a genetic study, SNPs rs7041 and rs2060793 of the GC gene in vitamin D-deficient women were associated with an increased risk of developing PCOS in a population of Indian women [108]; however, a case-control study of genotypes and allele frequencies of VDBP polymorphisms (rs4588, rs7041, and rs22822679) found no differences between women with and without PCOS in a sample of 1359 women [109].