Survival in pan-kidney cohort (KICH+KIRC+KIRP), lower grade glioma, mesothelioma, colorectal adenocarcinoma was similarly affected by IGFBP-3 to a lesser extent (FDR = 1.74∙10−6 (HR = 2.73), 1.25∙10−5 (HR = 2.36), 1.22∙10−3 (HR = 2.98), 3.87∙10−3 (HR = 2.20), respectively) (Figure 6B,C). The gene discussed is IGFBP3; the disease is central nervous system cancer.