EDN1 and fetal growth restriction: Over the past decade, omic sciences that are aimed to epigenetics, transcriptomics, GWAS (Genome-wide associations), proteomics, and metabolomics have allowed to further characterize the molecular mechanisms underlying these conditions, and several placental genes such as VEGF, sFlt1, ENG, EDN1, IGFBP1, and LEP have been identified on different clinical PE and/or IUGR phenotypes [13,14,18,30,31,32,33,34,35].