Even if results mainly support its use as a diagnostic and screening tool to detect early stages of pancreas cancer, it was observed that in the 75% of breast cancer patients the levels of circulating EXOs positive for GPC1 were higher than in healthy individuals; the data on breast cancer, though, did not support any specific correlation between the level of EXOs positive for GPC1 and breast cancer subtypes, maybe for a size too small of the observed group [117]. The gene discussed is GPC1; the disease is pancreatic neoplasm.