VEGFA and age-related macular degeneration: Closer to clinics, a comparative cost-effectiveness of therapy for age-related macular degeneration has been performed between Verteporfin (a ribonucleic acid aptamer targeting the vascular endothelium growth factor (VEGF) from Novartis Pharma AG) and Ranibizumab (a monoclonal antibody targeting a wider diversity of VEGF isoforms from Genentech Inc).