Notably, a simultaneous report by Krause et al. showed a role of CD44 in homing and repopulation of chronic myeloid leukemia (CML) stem cells, suggesting that both acute and chronic forms of myeloid leukemia may use CD44 for adhesive interactions of blasts to the marrow niche [25]. The gene discussed is CD44; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.