CD81 and malaria: However, host factors previously implicated in malaria LS infection, such as cluster of differentiation 81 (Cd81), protein kinase C zeta (Prkcz), and hepatocyte growth factor receptor (Hgfr) (Carrolo et al., 2003, Prudêncio et al., 2011, Silvie et al., 2006) were upregulated in both JM8.N4 and E14 cells after MBA differentiation.