PNPLA2 and infection: To avoid being confounded by difference in host genetic backgrounds contributing to variation in infection and parasite development between fibroblast lines, PNPLA2 knockdown was performed in healthy fibroblast line F011-11N-RM-01/02 (Control 1) and infected with P. berghei sporozoites to determine the role of PNPLA2 during LS infection (Figure S4).