PNPLA2 and hepatocellular carcinoma: In particular, we assessed the role of mouse Pnpla2, coding for adipose triglyceride lipase (ATGL), in P. berghei LS development in MBA-differentiated mouse ESCs, since preliminary small interfering RNA (siRNA) screening in Huh7 human hepatoma cells showed a negative impact on EEF development upon ATGL knockdown (see Results).