CD40LG and Cowden syndrome 1: The 13 newborns with CS diagnoses had the following findings: FTA-ABS test results positive for serum IgM (n = 10), positive serum RPR titers (n = 5), CSF findings (n = 3), very low (<1,500 g; n = 2) or extremely low (<1,000 g; n = 1) birth weight, clinical signs compatible with CS (n = 2), and cardiac anomaly (n = 1).