RPA3 and cancer: In addition, previous studies have demonstrated the expression of RPA1 and RPA2 are potential prognostic factors in multiple cancers,[17, 19] and likewise, RPA3 has been associated with survival of patients with gastric cancer,[20] hepatocellular cancer,[21] and NPC.[22] These findings suggest that RPA1 and other subunits of RPA complex might be important modulators for the progression of several human cancers.