In addition, previous studies have demonstrated the expression of RPA1 and RPA2 are potential prognostic factors in multiple cancers,[17, 19] and likewise, RPA3 has been associated with survival of patients with gastric cancer,[20] hepatocellular cancer,[21] and NPC.[22] These findings suggest that RPA1 and other subunits of RPA complex might be important modulators for the progression of several human cancers. This evidence concerns the gene RPA1 and gastric cancer.